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To our knowledge, malaria in Africa is very serious. Meanwhile, the RBM Partnership is also carrying out coordinated action towards ending malaria. In the process of infusion treatment, due to the lack of goods and materials, there is no precise instrument for monitoring, a situation that easily occurs blood reflux, affects the therapeutic effect, and is seriously or even life-threatening. This device is considered to use the heart valve principle in the infusion device combined with bionic design to prevent venous blood reflux. The Anti-Blood Reflux Device is structurally integrated with an infusion and is both easy to use and portable.