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R-GEN 100 is a 3D tabletop Bioprinter designed for highly accurate and repeatable printing of multiple materials. Combining up to 5 print tools with thermal control, different print technologies or multiples of the same print tool can be installed on one instrument, providing the user great flexibility to print from single paste formulations or direct from powder without the need for intermediate products. It can be used both in industry and research, for regenerative medicine, drug discovery, tissue engineering, and personalized medicine.