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The survey shows that there are 96% of accidents occurred in junior high schools because of students' carelessness. Therefore, schools must enhance their attitudes and knowledge about operational safety in the laboratory. Using the "Chemistry VR Lab" can improve learning effect and create a better experience, It can also change learners learning attitudes. Learners can try and experiment in the virtual world while they can't in the real world. It can not only enable the user to try but also teach the user how to do when encountering the emergency situation step by step.